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CHEM3011 Medicinal Chemistry

Later Year Course

Offered By Department of Chemistry
Academic Career Undergraduate
Course Subject Chemistry
Offered in First Semester, 2009 and First Semester, 2010
Unit Value 3 units
Course Description

Organic synthesis is integral to the process of drug development in the pharmaceutical industry. This course is designed to develop student understanding of key concepts of organic chemistry relevant to medicinal chemistry. Topics covered include, chemical reactivity, specificity and selectivity, how to plan and execute a synthesis, oxidation and reduction methods, organometallic reagents, olefin metathesis, radical and pericyclic reactions. Examples will highlight the application of synthetic chemistry to the assembly of complex molecules with biological activity of therapeutic interest.

Learning Outcomes

On satisfying the requirements of this course, students will have the knowledge and skills to:

1. recognise key chemical transformations used in the synthesis of biologically active molecules including oxidation and reduction, organometallic reactions, olefin metathesis, radical and pericyclic reactions
2. understand fundamental concepts associated with chemical transformations including reactivity, specificity and selectivity
3. work individually and with peers to evaluate, understand and describe real-world examples of the organic chemical synthesis of biologically active compounds and natural products
4. design a sequence of known and reliabe chemical transformations for the synthesis of organic compounds
Indicative Assessment

Assessment will be based on:

  • Two hour exam, including a component of literature-based review of synthetic chemistry (80%; LO 1, 2, 3, 4)
  • Group assignment involving the discussion and evaluation of a recent literature synthesis of a biologically active natural product (20%; LO 1, 2, 3)
Workload

Approximately 24 h lectures and 6 assignment tutorials, with students expected to devote equivalent out-of-class time on the assignment and for private study

Areas of Interest Chemistry
Requisite Statement

CHEM2202 and CHEM2203

Incompatibility CHEM3101
Science Group C
Academic Contact Mal McLeod

The information published on the Study at ANU 2009 website applies to the 2009 academic year only. All information provided on this website replaces the information contained in the Study at ANU 2008 website.

Updated:   13 Nov 2015 / Responsible Officer:   The Registrar / Page Contact:   Student Business Solutions