CHEM6011 Medicinal Chemistry
| Offered By | Department of Chemistry |
|---|---|
| Academic Career | Graduate Coursework |
| Course Subject | Chemistry |
| Offered in | First Semester, 2009 and First Semester, 2010 |
| Unit Value | 3 units |
| Course Description |
Organic synthesis is integral to the process of drug development in the pharmaceutical industry. This course is designed to develop student understanding of key concepts of organic chemistry relevant to medicinal chemistry. Topics covered include, chemical reactivity, specificity and selectivity, how to plan and execute a synthesis, oxidation and reduction methods, organometallic reagents, olefin metathesis, radical and pericyclic reactions. Examples will highlight the application of synthetic chemistry to the assembly of complex molecules with biological activity of therapeutic interest. The course builds on an identified strength of the Australian National University in the field of Organic Synthesis. Note: Graduate students attend joint classes with later year undergraduate students but are assessed separately. |
| Learning Outcomes |
On satisfying the requirements of this course, students will have the knowledge and skills to: 1. recognise key chemical transformations used in the synthesis of biologically active molecules including oxidation and reduction, organometallic reactions, olefin metathesis, radical and pericyclic reactions2. explain fundamental concepts associated with chemical transformations including reactivity, specificity and selectivity 3. work individually to evaluate, understand and describe real-world examples of the organic chemical synthesis of biologically active compounds and natural products 4. design a sequence of known and reliabe chemical transformations for the synthesis of organic compounds |
| Indicative Assessment |
Assessment will be based on:
|
| Workload | Approximately 24 h lectures and 6 assignment tutorials, with students expected to devote equivalent out-of-class time on the assignment and for private study |
| Course Classification(s) | AdvancedAdvanced courses are designed for students having reached 'first degree' level of assumed knowledge, which provide a deep understanding of contemporary issues; or 'second degree' and higher levels of knowledge; or for transition to research training programs. |
| Eligibility | Students must have a Bachelor of Science degree or equivalent with a major in chemistry with relevant experience or honours. Applicants with the equivalent of a pass degree may be admitted if they have a high level of relevant academic achievement. |
| Consent Required | Approval of the graduate program convener in chemistry. |
| Academic Contact | Dr Mal McLeod |
The information published on the Study at ANU 2009 website applies to the 2009 academic year only. All information provided on this website replaces the information contained in the Study at ANU 2008 website.
