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MATH6100 Bioinformatics and Biological Modelling

Offered By Department of Maths
Academic Career Graduate Coursework
Course Subject Mathematics
Offered in Second Semester, 2010 and Second Semester, 2011
Unit Value 6 units
Course Description

The course begins with a detailed discussion of sequence alignment algorithms that are critical for assessing the relatedness of DNA, RNA and amino acid sequences. We then proceed to studying Markov chains and hidden Markov models as important examples of biological models for such sequences. The main algorithms and several applications will be explained. Finally, a broad range of examples of applications of mathematics in biology, both at the molecular and macroscopic level, will be given. These may include current research being done at the ANU. The course is accompanied by computer lab sessions where we explore, in particular, major biological databases and sequence similarity search.

Learning Outcomes

On satisfying the requirements of this course, students will have the knowledge and skills to:

1. Understand basic models for the evolution of biological sequences.
2. Understand and apply basic probabilistic concepts such as probability spaces, conditional probability, Markov chains, and stationary distributions.
3. Understand the main principles of mathematical modelling in biology.

Indicative Assessment

Assignment 1: 25% Assignment 2: 25% Take home exam: 35% Home work: 15%

Course Classification(s) AdvancedAdvanced courses are designed for students having reached 'first degree' level of assumed knowledge, which provide a deep understanding of contemporary issues; or 'second degree' and higher levels of knowledge; or for transition to research training programs. and SpecialistSpecialist courses are designed for students having reached 'first degree' level of assumed knowledge, which provide for the acquisition of specialist skills; or 'second degree' and higher level of knowledge; or for transition to research training programs; or knowledge associated with professional accreditation.
Areas of Interest Mathematics
Eligibility Bachelor degree; with first year Maths.
Requisite Statement First year Maths is required. 
Consent Required Please contact admin.teaching.msi@anu.edu.au for consent to enrol in this course.
Programs Master of Mathematical Sciences

The information published on the Study at ANU 2010 website applies to the 2010 academic year only. All information provided on this website replaces the information contained in the Study at ANU 2009 website.

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