The course introduces the experimental techniques of X-ray crystallography and NMR spectroscopy for the analysis of the structure and dynamics of biological macromolecules. It also gives an introduction into the fundamental principals of protein structure and dynamics. Wherever possible quantitative examples will be given – students will be expected to solve numerical problems. The course is intended for graduate students who may want to acquire and use macromolecular structures.

To introduce graduate students to the concepts of structural biology as they pertain to chemistry. The course will introduce students to the experimental techniques of X-ray crystallography and NMR spectroscopy for the analysis of the structure and dynamics of biological macromolecules. It will also provide graduate students with an introduction into the fundamental principals of protein structure and dynamics.

PG Assessment:

• 50% written exam
• 30% eight short answer written exams at the beginning of each of 8 tutorials
• 20% assignment (on material related to that covered in the course but at a higher level)

UG Assessment:

• 60% written exam
• 40% eight short answer written exams at the beginning of each of 8 tutorials

24 lectures and 8 tutorials

Any 2nd Year Chemistry course or CHEM6008

CHEM3041

No prescribed text.