This course covers the principles of the transmission and expression of genetic information, in both prokaryotes and eukaryotes. Topics to be covered include: cell structure and function; DNA structure and packaging; DNA replication and repair; transcription; regulation of gene expression; RNA processing; protein synthesis and the genetic code; protein trafficking and degradation.   

Honours pathway option (HPO)

Entry to this option is subject to the approval of the course convener. Students who take this option complete extension inquiry-learning activities into each laboratory exercise (30%). These will include one or more of: data analysis, experimental design, literature research, formal laboratory report, oral presentation. These activities will reinforce generic skills taught in first year and will be essential for the third year inquiry-learning courses such as BIOL3174.

On satisfying the requirements of this course, students will have the knowledge and skills to:

1. Explain the basic processes involved in the expression of genetic information (DNA replication; mutagenesis and DNA repair; mRNA transcription and processing; gene regulation; protein synthesis and trafficking;  the cell cycle)
2. Understand the roles and functions of these processes
3. Predict outcomes when these processes are perturbed by mutation (genetic disease) or the use of inhibitors and drugs
4. Understand differences between gene organization in prokaryotes and eukaryotes
5. Interpret and analyse experimental and theoretical problems involving these processes

Assessment will be based on:

• Laboratory reports to apply knowledge to experimental/theoretical problem (30%; LO 1, 3, 4, 5)
• Tutorial tests to demonstrate mastery and understanding of content  (20%; LO 1, 2, 3, 4)
• Final exam to demonstrate understanding, interpretation and problem solving (50%; LO 1,2,3,4,5)

Two lectures per week; five laboratory sessions of up to four hours each; ten one-hour tutorials.

BIOL1004 and CHEM1101 (or CHEM1014/16)

BIOL2061