The aim of this course is to teach genomics, proteomics, metabolomics and phenomics using model organisms representing plants and animals. The course will cover recent developments in genetics, epigenetics, small RNAs, proteomics, gene expression, mutagenesis and mapping genes. An objective of the course will be to develop skills in experimental design within the context of learning about biology including: signal transduction, regulation of transcription and translation, cancer, aging, drought stress and metabolic pathways.

Note: Graduate students attend joint classes with undergraduates but are assessed separately.

On satisfying the requirements of this course, students will have the knowledge and skills to:

1. Describe recent advances in genomics, transcriptomics, metabolomics and proteomics.
2. Explain some of the current genomics technologies and illustrate how these can be used to study gene function.
3. Obtain and analyse information and data relating to specific genes using a number of general and plant-specific databases, bioinformatics principles and tools.
4. Locate and critically evaluate current scientific literature and discuss the important findings of these papers in writing.
5. Perform a range of practical techniques including DNA sequencing, real-time RT-PCR and proteomics.
6. Design a set of experiments to address a particular biological question.

Assessment will be based on:

• Laboratory/tutorial reports (45%; LO 1, 2, 3, 4, 5)
• Experimental design exercise (15%; LO 1, 2, 4, 6)
• Final exam (40%; LO 1, 2, 6)

Two lectures per week and up to twenty six hours of laboratory and computing sessions.

Requires Bachelor of Science or equivalent with a major in the field of biological sciences with relevant experience or academic achievement, AND specific knowledge in the area of cell and molecular biology.

BIOL8020